Voltammetric behavior of acebutolol on pencil graphite electrode: highly sensitive determination in real samples by square‑wave anodic stripping voltammetry
MetadataShow full item record
CitationLevent, A. (2017). Voltammetric behavior of acebutolol on pencil graphite electrode: highly sensitive determination in real samples by square‑wave anodic stripping voltammetry. Journal of the Iranian Chemical Society, 14, pp. 2495-2502. https://doi.org/10.1007/s13738-017-1184-z
In this work, an electrochemical investigation of acebutolol (ACE), a beta-blocker drug, was carried out in alkaline medium using pencil graphite (PG) electrode. In cyclic voltammetry, the compound displayed a reversible and adsorption-controlled oxidation peak. By using squarewave anodic stripping voltammetry, the oxidation peak current observed at +0.78 V showed a linear relationship with concentration at 0.4–7 nM interval in Britton–Robinson bufer (pH 10.0) and a detection limit of 0.09 nM. The relative standard deviation of 4.72% for the concentration level of 2.0 nM (n = 11) was also calculated. The PG electrode that is used for the frst time in this method was successfully applied to determine the ACE in pharmaceutical formulations and urine.
SourceJournal of the Iranian Chemical Society
The following license files are associated with this item: