Levent, Abdulkadir2021-03-222021-03-222017-08-22Levent, A. (2017). Voltammetric behavior of acebutolol on pencil graphite electrode: highly sensitive determination in real samples by square‑wave anodic stripping voltammetry. Journal of the Iranian Chemical Society, 14, pp. 2495-2502. https://doi.org/10.1007/s13738-017-1184-z1735-207Xhttps://doi.org/10.1007/s13738-017-1184-zhttps://link.springer.com/content/pdf/10.1007/s13738-017-1184-z.pdfhttps://hdl.handle.net/20.500.12402/2754In this work, an electrochemical investigation of acebutolol (ACE), a beta-blocker drug, was carried out in alkaline medium using pencil graphite (PG) electrode. In cyclic voltammetry, the compound displayed a reversible and adsorption-controlled oxidation peak. By using squarewave anodic stripping voltammetry, the oxidation peak current observed at +0.78 V showed a linear relationship with concentration at 0.4–7 nM interval in Britton–Robinson bufer (pH 10.0) and a detection limit of 0.09 nM. The relative standard deviation of 4.72% for the concentration level of 2.0 nM (n = 11) was also calculated. The PG electrode that is used for the frst time in this method was successfully applied to determine the ACE in pharmaceutical formulations and urine.eninfo:eu-repo/semantics/embargoedAccessAttribution-NonCommercial-ShareAlike 3.0 United StatesAcebutololPharmaceuticalPencil Graphite ElectrodeSquare-Wave Anodic Stripping VoltammetryArticle1424952502Q3Q3