Chemical constituents and biological activities of cirsium leucopsis, c. sipyleum, and c. eriophorum
Küçük Resim Yok
Tarih
2015-03-19
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Walter de Gruyter
Erişim Hakkı
info:eu-repo/semantics/openAccess
Attribution-NonCommercial-ShareAlike 3.0 United States
Attribution-NonCommercial-ShareAlike 3.0 United States
Özet
Two endemicCirsiumspecies,C. leucopsisDC. andC. sipyleumO. Schwarz, andC. eriophorum(L.) Scop. growing in Turkey were investigated to establish their secondary metabolites, fatty acidcompositions, and antioxidant and anticholinesterase potentials. Spectroscopic methods were usedto elucidate the structures of thirteen known compounds (p-hydroxy-benzoic acid, vanillic acid,cis-epoxyconiferyl alcohol, syringin, balanophonin, 1′-O-methyl-balanophonin, apigenin, kaempferol-3-O-β-D-glucopyranoside, kaempferol-3-O-α-L-rhamnopyranoside, taraxasterol, taraxasterol acetate,β-sitosterol,β-sitosterol-3-O-β-D-glucopyranoside).cis-Epoxyconiferyl alcohol and 1′-O-methyl-balanophonin were isolated for the first time fromCirsiumspecies. Palmitic acid (47.1 %) was foundto be the main fatty acid ofC. leucopsis, linoleic acid in bothC. sipyleum(42.1 %) andC. eriophorum(37.8 %). Assays ofβ-carotene bleaching, scavenging of 1,1-diphenyl-2-picrylhydrazyl (DPPH) freeradicals, 2,2-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium (ABTS) cation radicals,and superoxide anion radicals, as well as cupric reducing antioxidant capacity (CUPRAC) were usedto determine the antioxidant activities of the extracts and isolated compounds. Vanillic acid, balano-phonin, and kaempferol-3-O-α-L-rhamnopyranoside exhibited strong antioxidant activity. Taraxa-sterol was a potent inhibitor of acetyl- and butyrylcholinesterase activity, respectively.
Açıklama
Anahtar Kelimeler
Cirsium, Secondary Metabolites, Biological Activity
Kaynak
WoS Q Değeri
N/A
Scopus Q Değeri
Q3
Cilt
69
Sayı
9-10
Künye
Boğa, M., Köseoğlu Yılmaz, P., Barış Cebe, D., Fatima, M., Siddiqui, B. S., Kolak, U. (2015). Chemical constituents and biological activities of cirsium leucopsis, c. sipyleum, and c. eriophorum. Zeitschrift für Naturforschung C, 69 (9-10), pp. 381-390. https://doi.org/10.5560/znc.2014-0071
