Application of a pencil graphite electrode for voltammetric simultaneous determination of ascorbic acid, norepinephrine, and uric acid in real samples
Yükleniyor...
Tarih
2018-04-27
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
TÜBİTAK
Erişim Hakkı
info:eu-repo/semantics/openAccess
Attribution-NonCommercial-ShareAlike 3.0 United States
Attribution-NonCommercial-ShareAlike 3.0 United States
Özet
A pencil graphite electrode (PGE) was used for the simultaneous detection of ascorbic acid (AA), norepinephrine (NE), and uric acid (UA) by differential pulse voltammetry and cyclic voltammetry. The anodic peaks of AA,
NE, and UA in their mixture can be well separated in 0.1 M Britton–Robinson buffer solution at pH 4.0. The effects of
various experimental parameters such as pH, scan rate, and voltammetric parameters on the voltammetric response of
these compounds were investigated. Under optimum conditions, linear calibration graphs were obtained from the AA,
NE, and UA concentration ranges, which were 100–800 nM, 20–170 nM, and 40–175 nM, respectively. The detection
limits for AA, NE, and UA were 27 nM, 4 nM, and 10 nM in the form of a mixture at the PGE. This electrode shows great
analytical performance characteristics, corresponding repeatability and recovery for the simultaneous determination of
these compounds. PGE, which was used for the first time in this method, has been successfully applied for the assay of
UA in human urine samples with the aim of determining AA and NE in pharmaceutical drugs.
Açıklama
Anahtar Kelimeler
Pencil Graphite Electrode, Ascorbic Acid, Norepinephrine, Uric Acid, Simultaneous
Kaynak
WoS Q Değeri
N/A
Scopus Q Değeri
Q3
Cilt
42
Sayı
2
Künye
Levent, A., Önal, G. (2018). Application of a pencil graphite electrode for voltammetric simultaneous determination of ascorbic acid, norepinephrine, and uric acid in real samples. Turkish Journal of Chemistry, 42 (2), pp. 460-471. https://dx.doi.org/doi:10.3906/kim-1708-14.
