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Öğe New drug loading systems: Using two component gelling strategy(Ankara Üniversitesi, 2015) Çolak, Mehmet; Evcil, Murat; Barış Cebe, Deniz; Hoşgören, HalilÖğe Asymmetric organocatalytic efficiency of synthesized chiral β-amino alcohols in ring-opening of glycidol with phenols(Springer Nature, 2012-04-11) Aral, Tarık; Karakaplan, Mehmet; Hoşgören, HalilA series of novel chiral β-amino alcohols 3-5 and 7-10 were synthesized by regioselective ring opening of epoxides and chiral amines with a straightforward method in high yields (up to 99 %). Kinetic resolution of racemic glycidol with phenols was achieved by using chiral amino alcohols as organocatalysts. Amino alcohols 5, 8 and 10 exhibited the highest enantioselectivities with p-cresol, phenol, and p-methoxyphenol by 63, 65, 58 % ee, respectively. The moderate enantioselectivities were observed with catalyst 9b towards all the nucleophiles (34-48 % ee). The ee values of the desired 3-aryloxy-1, 2-diols were determined by HPLC. This study presents an attractive tool for the synthesis of β-blockers and structurally complex molecules.Öğe Organogels as novel carriers for dermal and topical drug delivery vehicles(Kimyagerler Derneği, 2017) Barış Cebe, Deniz; Çolak, Mehmet; Hoşgören, HalilÖğe Düşük mol kütleli homo kiral bis amino alkol okzal amit jelatörler(Muğla Sıtkı Koçman Üniversitesi, 2012) Barış Cebe, Deniz; Kaya, Gülşen; Kaplan, Şeref; Çolak, Mehmet; Aydın, Haluk; Hoşgören, HalilÖğe Ibuprofen için yeni organojel formülasyonlar(Sakarya Üniversitesi, 2013) Çolak, Mehmet; Uzan, Serhat; Barış Cebe, Deniz; Aydın, Haluk; Hoşgören, HalilÖğe Potansiyel ilaç taşıyıcı sistem olarak homo kiral bis amino alkol okzalamit jelatörler(Kimyagerler Derneği, 2013) Barış Cebe, Deniz; Çolak, Mehmet; Kaplan, Şeref; Aydın, Haluk; Hoşgören, HalilÖğe Lizin bazlı yeni biyouyumlu malzeme sentezi ve uygulamaları(Bilkent Üniversitesi, 2014) Barış Cebe, Deniz; Çolak, Mehmet; Evcil, Murat; Hoşgören, HalilÖğe New drug delivery systems: Using two-component gelling system as a highly tunable soft materia(Bahçeşehir Üniversitesi, 2016) Çolak, Mehmet; Evcil, Murat; Barış Cebe, Deniz; Hoşgören, HalilÖğe Homochiral bis aminoalcohol oxalamide organogels in fatty acid esters as transdermal penetration enhancers as matrix for transdermal transport of drugs(Ankara Üniversitesi, 2012) Çolak, Mehmet; Kaplan, Şeref; Kaya, Gülşen; Barış Cebe, Deniz; Aydın, Haluk; Hoşgören, Halil
