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Öğe The changes in the serum, liver, kidney protein and genomic DNA profiles in rats treated with 7,12-Dimethylbenz(A) anthracene and Plantago major L.(RJPBCS, 2014-01) Berber, İsmet; Ekin, Suat; Levent, Abdulkadir; Oto, Gökhan;In the study, the changes in the serum, liver, kidney protein and genomic DNA profiles in Wistar albino rats administrated to 7,12-dimethylbenz(a)anthracene (DMBA) and Plantagomajor L. were investigated. SDS-PAGE profiling of the serum proteins showed that the levels of two proteins molecular weighing 140.8 kDa and 46.8 kDa were significantly lower on the 0th day of treatment than on the 60th day of application in the groups. Furthermore, two proteins (34.5 and 22.3 kDa) were solely present in DMBA-treated liver cell lysates. On the contrary, the kidney protein profiles did not show significant banding variations in groups. Genomic DNA analysis also confirmed that DNA extracted from liver and kidney cells did not fragment in any of the groups after the 60th study day. The proteins 34.5 and 22.3 kDa in liver cell lysates at the 60th day in DMBA-treated group could be extra-prognostic indicators for severe DMBA toxicity.Öğe Influence of yogurt adding on physicochemical and sensorial properties of some lettuce types(WFL Publisher, 2013) Tarakçı, Zekai; Uǧur, Atnan; Temiz, Hasan; Dağ, BeşirThe aim of this study was to investigate the effects of adding yogurt and roasting treatment on some physicochemical, L*, a* and b* colour values and organoleptic acceptability properties of lettuce types. The 10 different lettuce varieties included kasam, mangano, robinson, olenka, arapsaçi{dotless}, red leaf, lolorosso, red salat, palamet and salanova were used. After cleaning and cutting into 0.5 mm, the lettuces were roasted with equal amount added yogurt for about 5 min and then applied to the mixing process. There were significant differences in dry matter and pH values between the lettuces added yogurt and raw lettuces. While dry matter of lettuces was increased significantly with yogurt, the pH levels were decreased. The whiteness values (L*) for lettuces have caused significant differences by adding yogurt and roasting applications. L* values of control sample without lettuces were significantly higher than the samples prepared by adding yogurt to lettuces. Lettuce types had a significant effect on the L* colour of samples. The lettuces were a significant a* color values between before and after roasting. After adding yogurt to lettuces; b* values of kasam, robinson and olenka colour values were significantly higher than the other samples prepared by adding yogurt to lettuce types. The lowest overall acceptability scores were detected for olenka, robinson and lolorosso lettuce types while the highest overall acceptability scores were detected for arapsaci, red salat and salanova lettuce types, which were common use in Turkish meals.Öğe Determination of Cu contamination in some spring and mineral waters around van by AAS after enrichment of activated carbon(Medwell, 2011) Dağ, Beşir; Kılıçel, FevziSome trace metal contamination in water is a major component in the determination of water quality. In order to supply qualify water for health of human being, terrestiral and aquatic animals is very important. Apparently, tap water and spring water qualities in many countries are effected by industrilization and over population. The main aim of this study was to detect copper metal concentration in some spring and mineral water around Van by means of Atomic Absorption Spectrometer after enrichment of activated carbon. Spring and mineral water samples were collected some different parts of city. These mineral and spring water samples were determined by a simple preconcentration method which is called activated carbon enrichment. The metal analysis was done to detect copper element. It was compared the results with standarts for drinking water quality of World Health Organization (WHO) and Europian Union drinking water standarts. As a result, copper level in the spring and mineral water around Van were generally suitable for the both criterias of World Health Organization (WHO) and Europian Union drinking water.Öğe Synthesis of rigid and C2-symmetric pyridino-15-crown-5 type macrocycles bearing diamide–diester functions: enantiomeric recognition for chiral primary organoammonium perchlorate salts(Elsevier, 2014-03-15) Şeker, Sevil; Barış Cebe, Deniz; Arslan, Nevin; Turgut, Yılmaz; Pirinççioğlu, Necmettin; Toğrul, MahmutFour novel C2-symmetric macrocyclic compounds with a pyridine function and possessing amide and ester lingeages were prepared. The enantiomeric discrimination abilities of these macrocycles against α-phenylethylammonium and α-(1-naphthyl)ethylammonium perchlorate salts were measured by standard 1H NMR titration techniques in DMSO-d6. A binding constant ratio of 31 (Kbind(S)/Kbind(R)) for two enantiomers of α-(1-naphthyl)ethylammonium salt with the macrocyclic host (S,S)-4 bearing phenyl arms was observed, which corresponds to an enantiomeric discrimination of approximately 94%. Molecular dynamic calculations were performed for some of the supramolecular complexes to in order to gain insight into the mode of molecular recognition between the macrocyclic compounds and ammonium salts; these results were consistent with experimental observations, which may be relevant to those in biochemical processes occurring in organisms.Öğe Synthesis and characterization of a new difunctional ligand and its metal complexes: An experimental, theoretical, cyclic voltammetric, and antimicrobial study(Taylor & Francis, 2015-07-29) Baykara, Hacı; İlhan, Salih; Öztomsuk, Abdussamet; Seyitoğlu, Mehmet Salih; Levent, Abdulkadir; Okumuş, Veysi; Dündar, AbdurrahmanA new difunctional Schiff base ligand and its some metal complexes were synthesized. The compounds were characterized by elemental analysis, 1H-NMR, 13C-NMR, FT-IR, UV-VIS, magnetic susceptibility measurements, molar conductivity measurements, and thermal gravimetric analysis techniques. Additionally, DPPH scavenging, metal chelating and antibacterial activity of compounds were examined via in vitro methods. The lowest DPPH scavenging activity observed by Co(II) as 36.28% and highest was ligand as 52.00%. A cyclic voltammetric study was also carried out to determine redox potentials of the compounds. Some theoretical studies such as 1H-NMR, HOMO-LUMO, and mapped electron density of the ligand were also carried out successfully.Öğe Hypericum perforatum L protective effects on fatand water soluble vitamins after administration of 7 12 dimethylbenz a anthracene in rats(Austin Publications, 2014-02) Levent, Abdulkadir; Oto, Gökhan; Ekin, Suat