Voltammetric behavior of acebutolol on pencil graphite electrode: highly sensitive determination in real samples by square‑wave anodic stripping voltammetry
Yükleniyor...
Tarih
2017-08-22
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Iranian Chemical Society
Erişim Hakkı
info:eu-repo/semantics/embargoedAccess
Attribution-NonCommercial-ShareAlike 3.0 United States
Attribution-NonCommercial-ShareAlike 3.0 United States
Özet
In this work, an electrochemical investigation
of acebutolol (ACE), a beta-blocker drug, was carried out
in alkaline medium using pencil graphite (PG) electrode. In
cyclic voltammetry, the compound displayed a reversible
and adsorption-controlled oxidation peak. By using squarewave anodic stripping voltammetry, the oxidation peak current observed at +0.78 V showed a linear relationship with
concentration at 0.4–7 nM interval in Britton–Robinson
bufer (pH 10.0) and a detection limit of 0.09 nM. The relative standard deviation of 4.72% for the concentration level
of 2.0 nM (n = 11) was also calculated. The PG electrode
that is used for the frst time in this method was successfully
applied to determine the ACE in pharmaceutical formulations and urine.
Açıklama
Anahtar Kelimeler
Acebutolol, Pharmaceutical, Pencil Graphite Electrode, Square-Wave Anodic Stripping Voltammetry
Kaynak
WoS Q Değeri
Q3
Scopus Q Değeri
Q3
Cilt
14
Sayı
Künye
Levent, A. (2017). Voltammetric behavior of acebutolol on pencil graphite electrode: highly sensitive determination in real samples by square‑wave anodic stripping voltammetry. Journal of the Iranian Chemical Society, 14, pp. 2495-2502. https://doi.org/10.1007/s13738-017-1184-z
