Electrochemical determination of melatonin hormone using a boron-doped diamond electrode
Yükleniyor...
Tarih
2012-01
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier
Erişim Hakkı
info:eu-repo/semantics/embargoedAccess
Attribution-NonCommercial-NoDerivs 3.0 United States
Attribution-NonCommercial-NoDerivs 3.0 United States
Özet
In this study, a boron-doped diamond electrode was used for the electroanalytical determination of melatonin in the pharmaceutical tablet and urine samples by square-wave voltammetry. Melatonin yielded a well-defined voltammetric response in Britton-Robinson buffer, pH 3.0 at + 0.88 V (vs. Ag/AgCl). Using the optimal square-wave voltammetry conditions, the oxidation peak was used to determine melatonin in the concentration range of 5.0 × 107 M to 4.0 × 106 M (r = 0.998, n = 8), a detection limit of 1.1 × 107 M (0.025 μg/mL) and relative standard deviation was 2.06% at the 2.0 × 106 M level (n = 10). Recoveries of melatonin were in the range of 97.67–105%, for both tablet and spiked human urine samples.
Açıklama
Anahtar Kelimeler
Melatonin, Boron-Doped Diamond Electrode, Square-Wave Voltammetry, Tablet, Urine
Kaynak
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
21
Sayı
Künye
Levent, A. (2012). Electrochemical determination of melatonin hormone using a boron-doped diamond electrode. Diamond and Related Materials, 21 , pp. 114-119. https://doi.org/10.1016/j.diamond.2011.10.018.
