Plantago major protective effects on antioxidant status after administration of 7,12-dimethylbenz(a)anthracene in rats

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dc.authorid0000-0001-7310-7800en_US
dc.authorid0000-0002-6502-5028en_US
dc.authorid0000-0003-2754-6030en_US
dc.authorid0000-0001-5792-419Xen_US
dc.authorid0000-0002-5836-5438en_US
dc.contributor.authorOto, Gökhan
dc.contributor.authorEkin, Suat
dc.contributor.authorÖzdemir, Hülya
dc.contributor.authorDemir, Halit
dc.contributor.authorYaşar, Semih
dc.contributor.authorLevent, Abdulkadir
dc.contributor.authorBerber, İsmet
dc.contributor.authorKaki, Barış
dc.date.accessioned2021-03-23T12:10:15Z
dc.date.available2021-03-23T12:10:15Z
dc.date.issued2011en_US
dc.departmentBatman Üniversitesi Fen - Edebiyat Fakültesi Kimya Bölümüen_US
dc.description.abstractAim: The present study was designed to evaluate effects of Plantago major extract on oxidative status in Wistar albino rats administrated 7,12-dimethylbenz(a)anthracene (DMBA). Methods: Rats were divided into three equal groups of 6 animals each: Group 1 controls, group 2 treated with DMBA (100 mg/kg, single dose) and group 3 receiving the DMBA and the aqueous extract at 100 mg/kg/d for 60 days. Results: Significant decrease in catalase (P<0.05), carbonic anhydrase (p≤0.01), reduced glutathione (GSH) (P<0.01) and total protein (P<0.01) values was observed in the DMBA group compared with the healthy controls and DMBA + Plantago major groups. Conclusion: The results suggest preventive effects of Plantago major on DMBA induced oxidative damage in Wistar albino rats that might be due to decreased free radical generation.en_US
dc.identifier.citationOto, G., Ekin, S., Özdemir, H., Demir, H., Yaşar, S., Levent, A., Berber, İ., Kaki, B. (2011). Plantago major protective effects on antioxidant status after administration of 7,12-dimethylbenz(a)anthracene in rats. Asian Pacific Journal of Cancer Prevention, 12 (2), pp. 531-535.en_US
dc.identifier.endpage535en_US
dc.identifier.issn1513-7368
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage531en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12402/2774
dc.identifier.volume12en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherAsian Pacific Organization for Cancer Preventionen_US
dc.relation.journalAsian Pacific Journal of Cancer Preventionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-sa/3.0/us/*
dc.subjectAntioxidanten_US
dc.subjectDMBAen_US
dc.subjectLipid Peroxidationen_US
dc.subjectPlantago Majoren_US
dc.subjectRaten_US
dc.titlePlantago major protective effects on antioxidant status after administration of 7,12-dimethylbenz(a)anthracene in ratsen_US
dc.typeArticleen_US

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Fen - Edebiyat Fakültesi, Kimya Bölümü, Makale Koleksiyonu
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