Protective effect of Hypericum perforatum L. on serum and hair trace elements in rats 7,12-dimethylbenz[a]anthracene-induced oxidative stress

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dc.authorid0000-0002-6502-5028en_US
dc.authorid0000-0002-9587-096Xen_US
dc.authorid0000-0001-7310-7800en_US
dc.authorid0000-0001-5792-419Xen_US
dc.contributor.authorEkin, Suat
dc.contributor.authorYardım, Yavuz
dc.contributor.authorOto, Gökhan
dc.contributor.authorLevent, Abdulkadir
dc.contributor.authorÖzgökçe, Fevzi
dc.contributor.authorKusman, Tuba
dc.date.accessioned2021-03-23T11:41:01Z
dc.date.available2021-03-23T11:41:01Z
dc.date.issued2012-02-08en_US
dc.departmentBatman Üniversitesi Fen - Edebiyat Fakültesi Kimya Bölümüen_US
dc.description.abstractThe study was designed to assess the effect of Hypericum perforatum L. (H.P) on serum and hair trace elements and mineral levels, oral administration of 7,12-dimethylbenz[a]anthracene (DMBA) induced oxidative stress in Sprague-Dawley female rats. Analysis of the trace element has been carried out using atomic absorption spectrophotometer method at end of 60th day. It has been found out that the DMBA group contained statistically lower Zn and Cr compared to the control group (p < 0.01) and (p < 0.05), Cu, Mg and Na contained higher than control group (p < 0.05), (p < 0.05) and (p < 0.05). In DMBA + H.P group, Zn higher and Na lower than DMBA group (p < 0.05), (p < 0.05), in hair samples Cd, K and Zn contained lower DMBA compared to the control group (p < 0.05), (p < 0.05) and (p < 0.05). In group DMBA + H.P, Cd was higher than DMBA group and Cr lowered accordance with control group (p < 0.05). The present study demonstrated significantly positive and beneficial effect of H.P on the concentration levels of Zn and Na in serum, also on Cd levels in hair between DMBA and DMBA + H.P groups.en_US
dc.identifier.citationEkin, S., Yardım, Y., Oto, G., Levent, A., Özgökçe, F., Kusman, T. (2012). Protective effect of Hypericum perforatum L. on serum and hair trace elements in rats 7,12-dimethylbenz[a]anthracene-induced oxidative stress. Environmental Toxicology and Pharmacology, 33 (3), pp. 440-445. https://doi.org/10.1016/j.etap.2012.01.010en_US
dc.identifier.endpage445en_US
dc.identifier.issn1382-6689
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ1en|US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage440en_US
dc.identifier.urihttps://doi.org/10.1016/j.etap.2012.01.010
dc.identifier.urihttps://hdl.handle.net/20.500.12402/2771
dc.identifier.volume33en_US
dc.identifier.wosqualityQ2en_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.isversionof10.1016/j.etap.2012.01.010en_US
dc.relation.journalEnvironmental Toxicology and Pharmacologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subjectTrace Elementen_US
dc.subjectDMBAen_US
dc.subjectHypericum Perforatumen_US
dc.subjectSerumen_US
dc.subjectHairen_US
dc.titleProtective effect of Hypericum perforatum L. on serum and hair trace elements in rats 7,12-dimethylbenz[a]anthracene-induced oxidative stressen_US
dc.typeArticleen_US

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