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Öğe The effect of Plantago major Linnaeus on serum total sialic acid, lipid-bound sialic acid, some trace elements and minerals after administration of 7,12-dimethylbenz(a)anthracene in rats(SAGE, 2012-04) Oto, Gökhan; Ekin, Suat; Özdemir, Hülya; Levent, Abdulkadir; Berber, İsmetThe present study was designed to evaluate the effect of Plantago major Linnaeus (PM) extract on serum total sialic acid (TSA), lipid-bound sialic acid (LSA), some trace elements (copper (Cu), zinc (Zn) and iron) and mineral levels (magnesium, calcium and sodium) in Wistar albino rat administrated 7,12-dimethylbenz(a)anthracene (DMBA). Rats were divided into three equal groups (n = 6). Group I comprised the control group, group II was treated with DMBA (100 mg/kg, single dose) and group III was treated with DMBA (100 mg/kg single dose) and aqueous extract of PM 100 mg/kg/day for 60 days. After 60 days, statistical analyses showed that TSA and LSA levels in DMBA and DMBA + PM groups were significantly higher compared to the control group (TSA: p < 0.01, p < 0.05; LSA: p < 0.05, p < 0.05, respectively). Serum Zn levels were decreased in subjects treated with DMBA (p < 0.01) and DMBA + PM (p < 0.05) compared to the control group values. Serum Cu levels were increased in DMBA group and PM-treated group compared to the control group values. The results of this investigation showed that the levels of TSA and LSA changed significantly, which are sensitive markers for detecting the toxic effects of DMBA. On the other hand, observed decline in Zn levels in rats from DMBA + PM group might be due to decreased generation of free radicals and oxidative stress. Results from this study suggest that PM may be partially effective in preventing carcinogenesis initiated by environmental carcinogen DMBA.Öğe Fluorescence properties and electrochemical behavior of some schiff bases derived from n-aminopyrimidine(Springer Nature, 2014-03) Gülcan, Mehmet; Doğrul, Ümit; Öztürk Ürüt, Gülsiye; Levent, Abdulkadir; Akbaş, EsvetA series of Schiff bases (L 1, L 2 and L 3 ) were prepared by refluxing aromatic aldehydes with N-Aminopyrimidine derivatives in methanol and ethanol. The structures of synthesized compounds were characterized by FTIR, 1H NMR, 13C NMR and microanalysis. The electrochemical behaviors of the Schiff base ligands were also discussed. Moreover, the evaluation of absorption and emission properties of the structures were carried out in five different solvents. The products show visible absorption maxima in the range of 304-576 nm, and emission maxima from 636 to 736 nm in all solvents tested.Öğe The changes in the serum, liver, kidney protein and genomic DNA profiles in rats treated with 7,12-Dimethylbenz(A) anthracene and Plantago major L.(RJPBCS, 2014-01) Berber, İsmet; Ekin, Suat; Levent, Abdulkadir; Oto, Gökhan;In the study, the changes in the serum, liver, kidney protein and genomic DNA profiles in Wistar albino rats administrated to 7,12-dimethylbenz(a)anthracene (DMBA) and Plantagomajor L. were investigated. SDS-PAGE profiling of the serum proteins showed that the levels of two proteins molecular weighing 140.8 kDa and 46.8 kDa were significantly lower on the 0th day of treatment than on the 60th day of application in the groups. Furthermore, two proteins (34.5 and 22.3 kDa) were solely present in DMBA-treated liver cell lysates. On the contrary, the kidney protein profiles did not show significant banding variations in groups. Genomic DNA analysis also confirmed that DNA extracted from liver and kidney cells did not fragment in any of the groups after the 60th study day. The proteins 34.5 and 22.3 kDa in liver cell lysates at the 60th day in DMBA-treated group could be extra-prognostic indicators for severe DMBA toxicity.Öğe Ag-doped HfO2 thin films via sol–gel dip coating method(Springer Nature, 2019-10-01) Pakma, Osman; Kaval, Şehmus; Kari̇per, İshak AfşinIn this study, undoped and Ag-doped HfO2 thin films were deposited on glass substrates by means of sol–gel dip coating method. These films were then thermally annealed at 500 °C for 1 h. The structural and optical properties of undoped and Ag-doped HfO2 thin films were characterized by X-ray diffraction, UV–Vis spectrometry and scanning electron microscope. The results of this analysis were compared and interpreted with the results obtained in literature by various methods of coating with HfO2. The X-ray diffraction peaks of the films paired with monoclinic HfO2 crystalline peaks. The refractive indices of the films decreased with doping Ag, at 500 nm wavelengths. The optical band gap values of Ag-doped HfO2 thin films increased with doping Ag. The porous structures were observed on the surface films, especially with 5% Ag doping.Öğe Laws doku enerji ölçümü tabanli k-NN siniflandirici modeli ile iris tanima sistemi(IEEE, 20013-06-13) Acar, Emrullah; Özerdem, Mehmet SiraçBiyometrik tanıma teknolojisi genellikle çok pahallı ve son derece önemli güvenlik uygulamaları ile ilişkili olmuştur.İris tanıma sistemi, etkili biyometrik tanımasistemlerinden biridir. Bu çalışmada, farklı insanlardan elde edilen gözimgelerininiçerdiği irisdokuözelliklerinegörekişilerin tanınmasıamaçlanmıştır. İmgeler CASIAiris veritabanındanelde edilmiştir. İmge dokusuna duyarlı yeni yöntemlerdenbiri olanLawsDoku Enerji Ölçümü (Laws TEM) kullanılarak, iris dokusunun belirli yerelalanlarındanöznitelik vektörleri elde edilmiştir. kEn Yakın Komşu (k-NN) sınıflandırıcıparametrelerinden komşu sayısı(k) farklı değerlerde alınarak, elde edilen öznitelik vektörleri k-NN sınıflandırıcısı ile ayrıştırılmıştır. Farklı komşu sayılarına göre sisteminperformans değerlerikarşılaştırılmıştır. Sonuç olarak en yüksek ortalama performans,k-NNsınıflandırıcısınınk=1ve 2komşularıyapısında % 80.74olarak gözlemlenmiştir.Öğe Fuel properties of biodiesels produced from blends of canola oil and animal tallow(SILA SCIENCE, 2011-04) Adin, Hamit; Altun, Şehmus; Yaşar, FevziBiodiesel is an alternative diesel fuel that can be produced from renewable feedstocks such as vegetable oil or animal fats by transesterification with methanol for using in diesel engines. The viscosity and density of biodiesel fuels are important parameters due to being key fuel properties for injection and combustion process of diesel engines. These fuel properties mainly depend on the feedstock which is used in the biodiesel production. Also, lubricity is an important for diesel engine fuels due to the fuel injection systems are lubricated by the fuel itself. In this study, the blends containing 0, 25, 50, 75 and 100% of food-grade canola oil/inedible animal tallow in volume basis were prepared and converted into methyl esters by base-catalyzed transesterification. Effect of canola oil ration in the feedstock on the viscosity, density and lubricity were investigated. Lubricity was determined using the high-frequency reciprocating rig (HFRR) test. Experimental results showed that the kinematics viscosity of increased as animal tallow ratio increased in the feedstock, as animal tallow itself is more viscous than canola oil. Also, density did not change much when blended feedstocks were used. Besides, it was observed that lubricity of biodiesel fuels from blended feedstocks was slightly get worse compared with pure biodiesels.Öğe Kızıltepe tarımsal alan i̇mgeleri̇ni̇n gabor dalgacik dönüşümü i̇le sınıflandırılması(IEEE, 2012-05-30) Acar, Emrullah; Özerdem, Mehmet SiraçBu çalışmada, Kızıltepe (Mardin) tarım alanlarına ilişkin imgelerin, bitkinin farklı gelişim dönemlerine (ekim dönemi, az gelişmiş dönem, tam gelişmiş dönem ve hasat dönemi) göre sınıflandırılması amaçlanmıştır. İmgeler TARİT (Tarımsal Rekolte İzleme ve Tahmin Sistemi) projesi kapsamında kurulan istasyonlardan elde edilmiştir. İmge dokusuna duyarlı olan yöntemlerden Gabor Dalgacık Dönüşümü (GDD) kullanılarak, ürünün gelişim sürecine ilişkin imgelerin öznitelik vektörleri elde edilmiştir. Bu yöntem ile elde edilen öznitelik vektörleri ayrı ayrı sınıflandırıcılarda test edilerek, elde edilen performans sonuçları karşılaştırılmıştır. Sınıflandırıcı olarak Çok Katmanlı Algılayıcı (MLP) ve k-En Yakın Komşu (k-NN) yöntemleri kullanılmıştır. Sonuç olarak en yüksek ortalama performans, MLP sinir ağının 24-35-4 ağ yapısında % 98.01 olarak gözlemlenmiştir.Öğe Determination of fatigue life of the unidirectional GFRP/Al hybridcomposite laminates(Elsevier, 2019-06-01) Deniz, Mehmet Emin; Aydin, FıratThis paper investigates the effects of loading rate andfiber orientation on the fatigue behavior of the uni-directional glass-fiber reinforced-plastic/aluminum (GFRP/Al) hybrid laminated (GLARE-2) plates. Fatigue testswere performed at three kinds of stress ratios (R = 0.3, 0.1, and−0.1) on specimens with differentfiber or-ientations,θ= 0°, 15°, 30°, 45°, 60°, 75°, and 90°, in the GFRP layers. All the fatigue results to be presented inthis article were obtained in repeated tension-tension and tension-compression at stress ratios of 0.3, 0.1, and−0.1, and the results were compared with each other. It has been shown that the specimens have the highestfatigue life in thefiber orientation direction at R = 0.3 loading rate. Also, it has been shown that the fatigue lifeof the specimens decreases as the loading rate decreases.Öğe Electrochemical determination of melatonin hormone using a boron-doped diamond electrode(Elsevier, 2012-01) Levent, AbdulkadirIn this study, a boron-doped diamond electrode was used for the electroanalytical determination of melatonin in the pharmaceutical tablet and urine samples by square-wave voltammetry. Melatonin yielded a well-defined voltammetric response in Britton-Robinson buffer, pH 3.0 at + 0.88 V (vs. Ag/AgCl). Using the optimal square-wave voltammetry conditions, the oxidation peak was used to determine melatonin in the concentration range of 5.0 × 107 M to 4.0 × 106 M (r = 0.998, n = 8), a detection limit of 1.1 × 107 M (0.025 μg/mL) and relative standard deviation was 2.06% at the 2.0 × 106 M level (n = 10). Recoveries of melatonin were in the range of 97.67–105%, for both tablet and spiked human urine samples.Öğe Preparation, spectral studies, theoretical, electrochemical and antibacterial investigation of a new Schiff base and its some metal complexes(Elsevier, 2014-10-05) İlhan, Salih; Baykara, Hacı; Seyitoğlu, Mehmet Salih; Levent, Abdulkadir; Özdemir, Sadin; Dündar, Abdurrahman; Öztomsuk, Abdussamet; Cornejo, MauricioA new Schiff base ligand, 1,6-Bis(2-(5-bromo-2-hydroxybenzylideneamino)-4-chlorophenoxy)hexane was synthesized. Some Schiff metal complexes of the new Schiff base were prepared by the reaction of some metal salts and the Schiff base. The complexes are non-electrolytes as shown by their molar conductivities (ΛM). The structures of metal complexes are proposed from elemental analysis, FT-IR, UV–vis, magnetic susceptibility measurements, molar conductivity measurements, mass spectra and thermal gravimetric analysis. In addition theoretical 1H NMR, HOMO–LUMO studies of the ligand; antimicrobial and cyclic voltammetric studies of the compounds were also carried out. In this study antioxidant and antibacterial activities of the compounds were examined via in vitro methods.
