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Öğe New voltammetric strategy for determination and electrochemical behaviors of metformin by pencil graphite electrode in the NaOH(Indian Chemical Society, 2020) Altunkaynak, Yalçın; Yavuz, Ömer; Levent, AbdulkadirMetformin(MET), an oral antidiabetic drug commonly used in the treatment of diabetes, is a drug that increases insulin sensitivity in the biguanide group [1]. MET shows its pharmacological effect by lowering the glucose level in the blood. In the literature research, there are studies using electrochemical techniques for the analysis of MET in biological fluid and drug forms[1-6]. In this study, the electrochemical properties of MET, one of the drugs used in the treatment of diabetes, were performed using a pencil graphite electrode in NaOH (0.1 M) solution. This compound was recorded with an irreversible and diffusion controlled adsorption oxidation peak at approximately +1.28 V by cyclic voltammetry. With square wave stripping voltammetry, it was observed that the peak current signals of MET in the concentration range of 2.76-24.8 µM in 0.1M NaOH solution increased linearly. At a concentration of 2.76 µM (n = 9), the limit of detection and relative standard deviation were calculated as 9.03 nM (1.495 ngmL-1 ) and 3.25 %, respectively. This method has been successfully applied for MET analysis in pharmaceutical preparations and urine samples without any separation.Öğe Experimental investigation of solar stills integrated with solar water heating collectors(Türk Isı Bilimi ve Tekniği Derneği, 2017-10-31) Argunhan, Zeki; El, Emin; Yıldız, Cengiz; Çakmak, GülşahSolar still is a more practical way of obtaining clean water. In this study, we aimed to improve the efficiency of solar still systems and obtain distilled water at the same time. For this purpose, 5 different solar still systems were designed. Type 1; conventional solar still, Type 2; conventional solar still integrated with solar water heating collector and run via natural convection, Type 3; conventional solar still integrated with solar water heating collector and tubular heat exchanger and run via natural convection, Type 4; conventional solar still placed with plate heat exchanger and integrated with solar water heating collector and run via natural convection, Type 5; conventional solar still placed with plate heat exchanger and integrated with solar water heating collector and run via forced convection. In this study, the experiments were carried out on the parameters influencing the performance, the amount of distilled water obtained, and the efficiency of experiment settings designed in different types; and finally the results were presented. The amount of distilled water and efficiency of conventional solar still were 2389 ml and 51.47%, respectively. Maximum total amount of water and efficiency from natural convection systems were obtained from Type 4, and the values calculated were found as to be 5788 ml and 55.91%. Maximum amount of distilled water and the efficiency were obtained by utilizing forced convection system were found as to be 6068 ml and 58.99%, respectively.Öğe Electronic properties of Cu/n-InP metal-semiconductor structures with cytosine biopolymer(Polska Akademia Nauk, 2015-09) Güllü, Ömer; Türüt, AbdülmecitThis work shows that cytosine biomolecules can control the electrical characteristics of conventional Cu/n-InP metal-semiconductor contacts. A new Cu/n-InP Schottky junction with cytosine interlayer has been formed by using a drop cast process. The current-voltage (I-V) and capacitance-voltage (C-V) characteristics of Cu/cytosine/n-InP structure were investigated at room temperature. A potential barrier height as high as 0.68 eV has been achieved for Cu/cytosine/n-InP Schottky diodes, which have good I-V characteristics. This good performance is attributed to the effect of interfacial biofilm between Cu and n-InP. By using C-V measurement of the Cu/cytosine/n-InP Schottky diode the diffusion potential and the barrier height have been calculated as a function of frequency. Also, the interface-state density of the Cu/cytosine/n-InP diode was found to vary from 2:24 × 1013 eV-1cm-2 to 5.56× 1012 eV-1 cm-2.Öğe Determination of trace metal and mineral levels in the tobacco and cigarette samples using by FASS(Chemical Society of Pakistan, 2013-04) Levent, Abdulkadir; Yardım, Yavuz; Demir, CengizCigarettes and tobacco products are consumed in large amounts by human beings in the world. Also, tobacco is one of the most important agricultural products in Turkey. The accumulation of heavy metals in tobacco leaves in accordance with a possible risk of transferring them to people by smoke is well known. This study was carried out to estimate trace metal and mineral levels in tobacco and cigarettes from Eastern and South-eastern Anatolia, Turkey. The analysis was done by flame atomic absorption spectrometry using dry ashing or wet digestion. Results obtained are in agreement with data reported in the literature.Öğe Effect of the air flow rate of blower on the performance of solar still(Türk Isı Bilimi ve Tekniği Derneği, 2015-06-01) Argunhan, Zeki; El, Emin; Yücel, Halit Lutfi; Çakmak, Gülşah; Yıldız, CengizSolar distillation is one of the important methods for water purification. This paper examines the performance of solar distillation system at different air flow rate. To increase the performance of distiller, artificial wind was created by fan and suitable wind speed was investigated to increase the amount of water distilled. The experiments were carried out in Elazığ climate conditions. In order to examine the effect of the wind speed on solar distillation system, two stills were manufactured with the size of 1000x1000 mm. One of them was the conventional still which was used as a reference. The other still was used to investigate experimentally the effect of the wind speed. Graphs were drawn for time-dependent changes in the amount of water distilled. It was found that that the productivity of the fan-still distiller was 14.7 % greater than that of a conventional still.Öğe New voltammetric strategy for determination and electrochemical behaviors of oxaliplatin by CPT-BDD electrode(Indian Chemical Society, 2020) Aslan, Mehmet; Levent, AbdulkadirVarious drugs made of metal compounds have been used in many diseases including cancer[1]. Studies on Oxaliplatin in the literature are these [2-6]. Oxaliplatin (OxPt), which is a platinum analogue with anti-cancer effect, was accentuated. OxPt is separated from cisplatin, one of analogues of platinum, by replacing 1,2-diaminocyclohexane with amine groups. In this study, a simple, fast and sensitive voltammetric method was developed for OxPt which shows anticancer effects with cytotoxic properties. The boron-doped diamond (BDD) electrode was activated electrochemically in cathodic direction in 0.5 M H2SO4 medium. Electrochemical properties of OxPt were investigated on BDD electrode surface using square-wave and cyclic voltammetry techniques. OxPt in Britton-Robinson(BR) buffer (pH 5.0) gave a well-determined voltammetric response at +1.01 V (vs. Ag/AgCl) using the square-wave voltammetry technique. The developed voltammetric technique was found to be linear with the concentration range of 1.0-3.5 μM in the BR (pH 5.0) medium and the limit of detection was 0.276 μM (0.109 μg mL-1 ). Recommended method was successfully applied to drug forms of OxPt.
