A detailed chemical and biological investigation of twelve allium species from Eastern Anatolia with chemometric studies

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Dosyalar

A Detailed Chemical and Biological Investigation of Twelve Allium Species from Eastern Anatolia with Chemometric Studies _ Enhanced Reader.pdf (13.9 MB)

Tarih

2020-11-14

Yazarlar

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Wiley-Blackwell

Erişim Hakkı

info:eu-repo/semantics/embargoedAccess
Attribution-NonCommercial-ShareAlike 3.0 United States

Özet

Allium species are widely consumed as food all over the world. The phenolic profile of ethanol extracts of aerial parts and roots of 12 Allium species, collected from five different Eastern Anatolia regions, were studied using LC-MS/MS. In vitro antioxidant, anticholinesterase, cytotoxic and antimicrobial activities were also tested. The multivariate analyses were performed using principal component and hierarchical cluster analyses. Seventeen of 27 standard compounds were detected in all Allium species. The major components were mainly identified as quinic acid, malic acid, vanillin, and p-coumaric acid. The aerial parts possessed better antioxidant activity than roots. Aerial parts of A. atroviolaceum, A. chrysantherum, A. kharputense, and A. shirnakiense exhibited high cytotoxic activity against DLD-1 colon cancer cell lines (IC50 12.5 μg/mL). A. shatakiense and A. vineale demonstrated good antimicrobial activity against S. aureus and E. coli (MIC 75 μg/mL). According to chemometric analysis, differences were detected between aerial parts and the roots. The aerial parts of A. atroviolaceum, A. chrysantherum, A. kharputense, and A. shirnakiense could be potent in the pharmaceutical industry while A. shatakiense and A. vineale in the food industry after further investigations.

Açıklama

Anahtar Kelimeler

Allium Species, Antioxidant Activity, Chemical Composition, Chemometry, Cytotoxic Activity

Kaynak

WoS Q Değeri

Q3

Scopus Q Değeri

Q2

Cilt

18

Sayı

1

Künye

İzol, E., Temel, H., Yılmaz, M. A., Yener, İ., Tokul Ölmez, Ö., Kaplaner, E., Fırat, M., Haşimi, N., Öztürk, M., Ertaş, A. (2020). A detailed chemical and biological investigation of twelve allium species from Eastern Anatolia with chemometric studies. Chemistry and Biodiversity, 18 (1). https://doi.org/10.1002/cbdv.202000560

Bağlantı

https://doi.org/10.1002/cbdv.202000560
 https://hdl.handle.net/20.500.12402/3044

Koleksiyon

Fen - Edebiyat Fakültesi, Biyoloji Bölümü, Makale Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu