Electroanalytical determination of progesterone hormone using borondoped diamond electrode
Küçük Resim Yok
Tarih
2020
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
ICNTC
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Attribution-NonCommercial-NoDerivs 3.0 United States
Attribution-NonCommercial-NoDerivs 3.0 United States
Özet
Progesterone is synthesized from pregnenolone, a derivative of cholesterol like other steroids.
It is a steroid hormone that has a vital importance in human and animal health. In case of
progesterone imbalance, it causes problems such as fertility and infertility. In this study,
electrochemical properties of Progesterone hormone Boron doped diamond (BDD) on
electrode surface were investigated in strongly acidic environment (HClO4 and H2SO4). A
fast, sensitive, selective and simple electroanalytical method was developed for cathodically
pre-treated BDD electrodes. A good linear analytical curve in the concentration range of 10
μM to 100 μM at a voltage value of +1.51 V (vs. Ag / AgCl) (after 120 s deposition at +0.1 V
voltage) in 0.5 M HClO4 using the square wave stripping technique for the quantification of
progesterone hormone obtained. The observability limit is 0.012 µM(3.77 µg L-1); The
relative standard deviation value (RSD) for the concentration of 3.1 µM (n = 11) was
calculated to be 4.87%. In addition, the developed voltammetric method has been successfully
applied to drug and blood serum.
Açıklama
Anahtar Kelimeler
Progesterone, Boron-Doped Diamond Electrode, Voltammetry, Serum
Kaynak
WoS Q Değeri
Scopus Q Değeri
Cilt
Sayı
Künye
Levent, A., Uçar, M. (2020). Electroanalytical determination of progesterone hormone using borondoped diamond electrode. 6th International Conference on New Trends in Chemistry, 17-18 October 2020.
