New voltammetric strategy for determination and electrochemical behaviors of metformin by pencil graphite electrode

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dc.authorid0000-0003-2562-9297en_US
dc.authorid0000-0001-5792-419Xen_US
dc.contributor.authorAltunkaynak, Yalçın
dc.contributor.authorYavuz, Ömer
dc.contributor.authorLevent, Abdulkadir
dc.date.accessioned2021-03-24T09:13:11Z
dc.date.available2021-03-24T09:13:11Z
dc.date.issued2020en_US
dc.departmentBatman Üniversitesi Fen - Edebiyat Fakültesi Kimya Bölümüen_US
dc.departmentBatman Üniversitesi Teknik Bilimler Meslek Yüksekokulu Kimya ve Kimyasal İşleme Teknolojileri Bölümüen_US
dc.description.abstractMetformin(MET), an oral antidiabetic drug commonly used in the treatment of diabetes, is a drug that increases insulin sensitivity in the biguanide group [1]. MET shows its pharmacological effect by lowering the glucose level in the blood. In the literature research, there are studies using electrochemical techniques for the analysis of MET in biological fluid and drug forms[1-6]. In this study, the electrochemical properties of MET, one of the drugs used in the treatment of diabetes, were performed using a pencil graphite electrode in NaOH (0.1 M) solution. This compound was recorded with an irreversible and diffusion controlled adsorption oxidation peak at approximately +1.28 V by cyclic voltammetry. With square wave stripping voltammetry, it was observed that the peak current signals of MET in the concentration range of 2.76-24.8 µM in 0.1M NaOH solution increased linearly. At a concentration of 2.76 µM (n = 9), the limit of detection and relative standard deviation were calculated as 9.03 nM (1.495 ngmL-1 ) and 3.25 %, respectively. This method has been successfully applied for MET analysis in pharmaceutical preparations and urine samples without any separation.en_US
dc.identifier.citationAltunkaynak, Y., Yavuz, Ö., Levent, A. (2020). New voltammetric strategy for determination and electrochemical behaviors of metformin by pencil graphite electrode. 6th International Conference on New Trends in Chemistry, 17-18 October 2020.en_US
dc.identifier.isbn9786056747656
dc.identifier.urihttps://hdl.handle.net/20.500.12402/2784
dc.language.isoenen_US
dc.publisherICNTCen_US
dc.relation.journal6th International Conference on New Trends in Chemistry, 17-18 October 2020en_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.subjectMetforminen_US
dc.subjectVoltammetryen_US
dc.subjectPencil Graphite Electrodeen_US
dc.subjectDrugen_US
dc.subjectUrineen_US
dc.titleNew voltammetric strategy for determination and electrochemical behaviors of metformin by pencil graphite electrodeen_US
dc.typeConference Objecten_US

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Fen - Edebiyat Fakültesi, Kimya Bölümü, Bildiri Metinleri Koleksiyonu
Batman Üniversitesi, Teknik Bilimler Meslek Yüksekokulu, Kimya ve Kimyasal İşleme Teknolojileri Bölümü, Bildiri Metinleri Koleksiyonu