Synthesis characterization and using some of schiff base ligands derived from 4 aminoantipyrine as an inhibitor

dc.authorid0000-0002-5208-355Xen_US
dc.authorid0000-0002-3670-3504en_US
dc.contributor.authorDağ, Beşir
dc.contributor.authorYaşar, Fevzi
dc.contributor.authorKızılkaya, Hakan
dc.date.accessioned2021-04-14T05:36:31Z
dc.date.available2021-04-14T05:36:31Z
dc.date.issued2017en_US
dc.departmentBatman Üniversitesi Fen - Edebiyat Fakültesi Kimya Bölümüen_US
dc.departmentBatman Üniversitesi Teknik Bilimler Meslek Yüksekokulu Kimya ve Kimyasal İşleme Teknolojileri Bölümüen_US
dc.description.abstractSchiff bases and their complexes are widely studied because of the increasing recognition of their role in biological systems. In azo methine derivatives, the C=N linkage is essential for biological activity; several azomethines were reported to possess remarkable antibacterial and antifungal, anticancer. With the increasing incidence of deep mycosis, there has been increasing emphasis on the screening of new and more effective antimicrobial drugs with low toxicity. These compounds were recently found to have significant antitumor and biological activity. Antipyrine derivatives are reported to exhibit analgesic and antiinflammatory effects, antiviral, antibacterial, and herbicidal activities, and have also been used as hair color additives and to potentiate the local anesthetic effect of Lidocaine. Transition metal complexes with ligands derived from 4-aminoantipyrine have significant biological activity. This prompted us to synthesize a new series of heterocyclic Schiff bases containing the antipyrinyl moiety. The present study reports synthesis and charaterization of Schiff bases derived from 1-phenyl-2,3-dimethyl-4-(N-2 hydroxybenzylidene)-3- pyrazolin-5-one and 1-phenyl-2,3-dimethyl-4-(N-2-hydroxynaphthylidene)-3-pyrazolin-5- one with 5-aminoisophtlalic acid [1-2]. These compounds were synthesized in high yield and characterized by SEM, FT–IR, 1H NMR and 13C NMR.en_US
dc.identifier.citationDağ, B., Yaşar, F., Kızılkaya, H. (2017). Synthesis characterization and using some of schiff base ligands derived from 4 aminoantipyrine as an inhibitor. International Conference on Engineering Technologies (ICENTE'17), 07-09 December 2017, Konya.en_US
dc.identifier.isbn9786056753558
dc.identifier.urihttps://hdl.handle.net/20.500.12402/2861
dc.language.isoenen_US
dc.publisherSelçuk Üniversitesien_US
dc.relation.journalInternational Conference on Engineering Technologies (ICENTE'17), 07-09 December 2017en_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSchiff Baseen_US
dc.subject4-Aminoantipyrineen_US
dc.titleSynthesis characterization and using some of schiff base ligands derived from 4 aminoantipyrine as an inhibitoren_US
dc.typeConference Objecten_US

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